Structure-Based Design
Structure-Based Design articles bring you up to speed on cutting-edge science that is actually used by researchers and industry experts to advance their fields.
Solving a 50-Year-Old Puzzle: AlphaFold 2 and Protein Folding
With the world watching on, DeepMind’s AlphaFold 2 outperformed every other team at the 2020 biennial protein-structure prediction challenge, also known as CASP 14. This was a significant step forward in the history of molecular [...]
Turning to Frog Skin for New Biologic Peptide Drugs
Looking for medicinal properties in natural compounds is the cornerstone of drug discovery, with many drugs on the market originating from or inspired by plant or animal metabolites. Frog skin secretions contain hundreds of biologically [...]
Liquid Phase Exfoliation of Graphite to Obtain Pure Graphene
Although graphene has some fascinating properties that have real-life applications, pure forms of this ‘wonder material’ is elusive. Although a multitude of manufacturing techniques are available, many of them have poor control over the shapes, [...]
Xeno Nucleic Acids: Research into Modified DNA
Many of us would have heard about DNA and RNA, the two naturally occurring nucleic acid polymers that store genetic material. But we may not be quite as familiar with xeno nucleic acids (XNAs). The [...]
Alpaca Antibodies are Shaking Up Medical Research
When it comes to medical research, we owe a great deal to animals. Lab rats, rabbits and even zebrafish have made contributions to the field. But one mammal that might not immediately come to mind [...]
Drug Tablet Design: Why Pills Come in So Many Shapes and Sizes
Have you ever wondered why drug tablets come in so many shapes, sizes, and even colors? Or why we sometimes have to take two pills instead of one? One of the last steps in drug [...]
