Structure-Based Design

Structure-Based Design articles bring you up to speed on cutting-edge science that is actually used by researchers and industry experts to advance their fields.

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Epigenetic Therapies for Treatment of Mental Disorders

February 8, 2019|

Mental health disorders range from anxiety and depression to schizophrenia and dementia, affecting a significant number of people worldwide. Current treatments tend to be short-term and carry high risks of withdrawal symptoms, among other adverse [...]

  • coronavirus outline of earth ftloscience post

Predicting Viral Outbreaks With Machine Learning

January 21, 2019|

Think about pandemics that have affected the human race, our history and even our culture. In recent times, viral outbreaks such as Zika, Ebola, HIV, and of course, Coronavirus, have caught us by surprise. Despite [...]

  • ligand docked in protein crystal structure ftloscience post

Molecular Docking: Bioinformatics in Drug Discovery

October 13, 2018|

Ever heard of the term bioinformatics? It’s an interdisciplinary field of science that combines different topics such as biology, computer science, mathematics and statistics. In a world where data is being generated at a faster [...]

  • CYP2E1 from CYP450 family of enzymes ftloscience post

Cytochrome P450 (CYP450) Enzymes: Meet the Family

July 27, 2018|

Metabolism is described as the series of chemical reactions required to sustain life. When it comes to drug metabolism, no one processes these chemicals better than the cytochrome P450 (CYP450) family of enzymes. Understanding key [...]

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New Approaches to Peptide-Based Drugs

April 3, 2017|

Pharmaceutical AbbVie’s Humira for the treatment of rheumatoid arthritis recorded sales of USD 16 billion in 2016 alone. As the pharmaceutical industry as a whole looks beyond small molecules to biologicals as therapeutics, there has [...]