Structure-Based Design
Structure-Based Design articles bring you up to speed on cutting-edge science that is actually used by researchers and industry experts to advance their fields.
Epigenetic Therapies for Treatment of Mental Disorders
Mental health disorders range from anxiety and depression to schizophrenia and dementia, affecting a significant number of people worldwide. Current treatments tend to be short-term and carry high risks of withdrawal symptoms, among other adverse [...]
Predicting Viral Outbreaks With Machine Learning
Think about pandemics that have affected the human race, our history and even our culture. In recent times, viral outbreaks such as Zika, Ebola, HIV, and of course, Coronavirus, have caught us by surprise. Despite [...]
How Drug Delivery Systems Are Transforming Neuromedicine
So you have discovered and synthesized a promising compound that could have significant therapeutic benefit, the next step would be to design a carrier that brings the drug to its proper location within the body. [...]
Molecular Docking: Bioinformatics in Drug Discovery
Ever heard of the term bioinformatics? It’s an interdisciplinary field of science that combines different topics such as biology, computer science, mathematics and statistics. In a world where data is being generated at a faster [...]
Cytochrome P450 (CYP450) Enzymes: Meet the Family
Metabolism is described as the series of chemical reactions required to sustain life. When it comes to drug metabolism, no one processes these chemicals better than the cytochrome P450 (CYP450) family of enzymes. Understanding key [...]
New Approaches to Peptide-Based Drugs
Pharmaceutical AbbVie’s Humira for the treatment of rheumatoid arthritis recorded sales of USD 16 billion in 2016 alone. As the pharmaceutical industry as a whole looks beyond small molecules to biologicals as therapeutics, there has [...]