Tagged: Drug Design

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Me-Too Drugs – Innovation Killers or Backbone of Drug Discovery?

‘Me-too’ or ‘follow-on’ drugs are the copycats of the drug discovery landscape. Taking inspiration from existing drugs and making small modifications to them, many new therapies have been developed in this manner. Despite their reputation for lacking novelty and innovation,...

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Strategies to Combat Antibiotic Resistance

Drug resistance is a common issue in drug discovery programs. After the long and expensive process of developing a drug, the last thing you want is to find that it doesn’t provide a therapeutic effect. Drug resistance is prevalent in...

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Medicinal Chemistry: Lead Modification and Optimization

Medicinal chemistry lays the foundation for the drug discovery process. A strong lead compound increases the chances of a pharmaceutical company developing a strong drug candidate, with better chances of success later on. Once a lead compound or ‘hit’ has...