Articles by Sean
The Asian Koel: All You Need to Know About THAT Noisy Bird
Woo-OOo! If you’ve lived in Asia, chances are you’ve been rudely awakened by the incessant cooing of this noisy bird. Both males and females have distinct calls (you’ve probably been annoyed by both); they look very different too! Learn all about the Asian Koel in this article. […]
How to Calculate the Rate Constant for Two-Compartment Model Drugs
When drugs enter our bodies, we can trace their behavior as they are absorbed into our bloodstream before being metabolized and removed. Most drugs follow linear processes (zero order, first order, second order, etc.) consistent with a one-compartment model. However, some drugs follow two-compartment models, which makes pharmacokinetic calculations like finding the rate constant more complicated. […]
Pros and Cons of Extended-Release Drug Products
Oral medication is often considered the ideal drug product as it is easy and convenient to administer. Extended-release tablets go one step further, extending the duration of the therapeutic effect. This article discusses how extended-release drug products work and their pros and cons. […]
An Overview of Tablet Excipients in Drug Formulation
Tablets (or pills) are made by compressing several chemical ingredients together. Apart from the active ingredient, the rest of the tablet comprises excipients or ‘non-active’ components. But even though they don’t directly provide a therapeutic benefit, excipients still play a significant role in the overall drug product. This resource highlights the different excipient types and their roles in tablet formulation. […]
Chromatography for Protein Analysis: Separation By Amino Acids
Proteins are biologically essential molecules consisting of specific combinations of amino acids. Reverse-phase chromatography is the gold standard for protein analysis, which separates them based on their proportion of hydrophobic amino acids. In this guide, we outline the mechanism of RP-HPLC protein analysis and highlight all 20 amino acids in chromatography. […]
Sean is a consultant for clients in the pharmaceutical industry and is a lecturer at a local university, where unfortunate undergrads are subject to his ramblings on chemistry and pharmacology.
