Structure-Based Design
Structure-Based Design articles bring you up to speed on cutting-edge science that is actually used by researchers and industry experts to advance their fields.
Demystifying AI in Drug Discovery: Chemical Synthesis
How can we use artificial intelligence (AI) to improve drug discovery and development? In this installment of our deep dive, we describe how AI and machine learning (ML) can improve chemical synthesis R&D, an area [...]
Demystifying AI in Drug Discovery: Primary and Secondary Screening
How can we use artificial intelligence (AI) to improve drug discovery and development? In this installment of our deep dive, we walk you through how AI can accelerate primary and secondary screening during the drug [...]
Drug Polymorphism: What it is and How to Control Polymorphs
Drug polymorphism occurs when a single chemical compound arranges itself into multiple crystal polymorphs under different conditions. It is a required field of study within pharmacology, as polymorphic forms can drastically change a drug’s safety [...]
Pros and Cons of Extended-Release Drug Products
Oral medication is often considered the ideal drug product as it is easy and convenient to administer. Extended-release tablets go one step further, extending the duration of the therapeutic effect. This article discusses how extended-release [...]
An Overview of Tablet Excipients in Drug Formulation
Tablets (or pills) are made by compressing several chemical ingredients together. Apart from the active ingredient, the rest of the tablet comprises excipients or ‘non-active’ components. But even though they don’t directly provide a therapeutic [...]
Choosing Between Hard and Soft Gel Capsules
When was the last time you swallowed a capsule? Capsules are a common drug delivery system used in various supplements and pharmaceutical products. How are they produced, what types of drugs can they contain, and [...]